A 24 year old right handed Pakistani woman who was eight weeks’ pregnant presented with a two day history of involuntary movements of her left arm, hand. According to Willson and Preece, the first description of chorea with onset during pregnancy (chorea gravidarum) was made by Horstius in The English. A pregnant woman, in her early 20s, presents with chorea following an emotional outburst. While the family members feel it to be a spirit.

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Published online Jun History of either rheumatic fever or chorea is suspected: Journal of Neurology, Neurosurgery, and Psychiatry. Gravidaurm Chorea gravidarum is a rare movement disorder of pregnancy.

Discussion Chorea is an involuntary abnormal movement characterised by abrupt, brief, non-rhythmic and non-repetitive movement of any limb, often associated with non-patterned facial grimaces. Three weeks prior to admission in our hospital, she had fever, sore throat and migrating polyarthralgia involving her left wrist followed by left knee joint. Tone was slightly reduced in upper limbs than lower limbs.

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The choreic movements may be caused by ischaemia or enhanced dopaminergic sensitivity grafidarum by increased female hormones during pregnancy. Post-streptococcal autoimmune disorders of the central nervous system.

[Chorea gravidarum].

Concomitant conditions Diabetes mellitus Systemic lupus erythematosus Thyroid disorders Maternal death Sexual activity during pregnancy.


AS is the obstetrician who carefully assisted in the patient delivering a healthy fetus. Group A streptococcal infection induces antibodies against the host neural tissues by a phenomenon called molecular mimicry. It mostly occurs in young patients; the average age is 22 years. Sign in to save your search Sign in to your personal account.

Chorea Gravidarum. | History of Medicine | JAMA Neurology | JAMA Network

This history was suggestive of an episode of rheumatic fever. The dopamine antagonists as the haloperidol and the chlorpromazine are useful to control the symptoms and are safe at lower doses.

Pathology of pregnancychildbirth and the puerperium O— This finding, as well as the persistence of the movement disorder, uncommon in chorea gravidarum, 2 suggests that the chorea of the patient was related to some other cause, perhaps a stroke. D ICD – Provenance and peer review: Retrieved from ” https: Create a free personal account to download free article PDFs, sign up for alerts, and more.

Acute fatty liver of pregnancy Gestational diabetes Hepatitis E Hyperemesis gravidarum Intrahepatic cholestasis of pregnancy. The patient had mild form of chorea which was aggravated by stress of her kin’s death and it subsided with one dose of long-acting pencillin, proper seclusion, rest, multivitamins and multimineral therapy.

Chorea gravidarum is grzvidarum rare movement disorder of pregnancy. Purchase access Subscribe to JN Learning for one year. BSL compiled the case report and submitted it online.


Correspondence to Bhagat Singh Lali, moc. Ectopic pregnancy Abdominal pregnancy Cervical pregnancy Interstitial pregnancy Ovarian pregnancy Heterotopic pregnancy Molar pregnancy Miscarriage Stillbirth.

Chorea gravidarum: a rarity in West still haunts pregnant women in the East

Privacy Policy Terms of Use. Differential diagnosis The differentials which were considered on history and examination were chorea gravidarum, systemic lupus erythematosus, primary anti-phospholipid antibodies, viral encephalitis, Huntington disease and Wilson disease. Willson P, Preece AA. However, she is still seen on follow-up and is on penicillin prophylaxis to prevent rheumatic heart disease.

It is associated with history of Sydenham’s chorea. The patient’s laboratory investigations did not show any evidence of recent streptococcal infection. The present patient was a case of rheumatic chorea without carditis with previous history of rheumatism but she was at risk of developing rheumatic heart disease in future. SU was the psychiatrist who was regularly advising the patient.

She had no antenatal health check-ups in this pregnancy. Laboratory investigations did not reveal anything interesting. Sign in to access your subscriptions Sign in to your personal account.